Personalised Cancer Medicine Flashcards 2022
![GIST](/static/images/biomarcadores/GIST.jpg)
![](/static/images/oncologia_ico_A.png)
Standard
![](/static/images/oncologia_ico_B.png)
Recommended
![](/static/images/oncologia_ico_C.png)
Currently not recommended
- CD 117/c-kit
- CD34
- Number of mitosis/50 large fields
- KIT and PDGFR mutations
- DOG1*
- BRAF, SDHB, NTRK**
- NF1
- RAS
- FGFR
** GIST wild type
The Recommended category is based on currentrecommendations by EMEA and FDA.
References:
1. Martin-Broto J, Martinez-Marín V, Serrano et al. Gastrointestinal stromal tumors (GISTs): SEAP-SEOM consensus on pathologic and molecular diagnosis. Clin Transl Oncol. 2017 May;19(5):536-545. doi: 10.1007/s12094-016-1581-2.